Academic Journal of Science, Technology and Education https://integrumpublication.org/index.php/ajste <p>The Academic Journal of Science, Technology and Education (ISSN 3041-7848) is a peer-reviewed, open-access international journal dedicated to advancing knowledge at the intersection of scientific inquiry, technological innovation, and educational practice. The journal publishes original research articles, reviews, and case studies that explore the integration of scientific methods, emerging technologies, and pedagogical strategies to enhance learning, teaching, and societal development. The journal welcomes interdisciplinary contributions from scholars, educators, technologists, and practitioners, aiming to foster critical dialogue and promote the application of research-based solutions to contemporary challenges in education and STEM fields.</p> Integrum en-US Academic Journal of Science, Technology and Education 3041-7848 The role of proteins in human health and diseases https://integrumpublication.org/index.php/ajste/article/view/298 This article examines the chemical structure, physicochemical properties, biological significance, and major functions of proteins in the human body. Particular attention is given to the four levels of protein organization, the formation of peptide bonds and protein synthesis, the role of enzymes as biological catalysts, and the classification and functions of complex proteins. The article also considers the structure of the viral capsid and its contribution to viral infection, as well as disorders associated with impaired protein metabolism. The analysis demonstrates that protein structure is closely related to biological function and that disturbances in protein metabolism or structure may contribute to disease development. Overall, proteins are essential for structural integrity, catalysis, transport, immune defense, movement, regulation, and maintenance of normal physiological processes. Shohjahon Rustamovich Nizomov Dilshod Rakhmonkulovich Elov Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0 2026-08-20 2026-08-20 2 8 3 7 Algorithm Design and Complexity Analysis of the Adaptive Trust- Aware Multi-Criteria Decision Method for Artificial Intelligence Systems https://integrumpublication.org/index.php/ajste/article/view/299 The increasing complexity of artificial intelligence (AI) systems requires decision- making methodologies that are not only adaptive but also capable of incorporating dynamic trust into the decision process. While the previously proposed Adaptive Trust-Aware Multi-Criteria Decision Method (ATMCDM) established a theoretical and mathematical foundation for trust- aware intelligent decision making, its practical effectiveness has not yet been comprehensively validated. This study presents an extensive experimental evaluation of the ATMCDM framework through comparative performance analysis, sensitivity analysis, and multiple case studies. The proposed validation framework compares ATMCDM with widely used multi-criteria decision- making methods, including AHP, TOPSIS, VIKOR, and ELECTRE, under dynamic and uncertain decision environments. Several quantitative evaluation metrics are employed to assess decision accuracy, adaptability, trust calibration, computational efficiency, and robustness. In addition, an ablation study is conducted to investigate the contribution of the trust adaptation mechanism to the overall decision quality. Experimental results demonstrate that ATMCDM consistently outperforms conventional MCDM approaches in environments where decision criteria, contextual information, and trust levels change over time. The adaptive weighting mechanism improves decision stability and robustness while maintaining computational feasibility for real-time applications. The findings confirm that trust-aware adaptation represents a significant enhancement to traditional decision- making models and provides a practical foundation for next-generation intelligent decision support systems. This study bridges the gap between theoretical modeling and practical implementation, contributing empirical evidence for the effectiveness of adaptive trust-aware decision methodologies in artificial intelligence. Nodirbek Abdumannob-o‘g‘li Yuldashev Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0 2026-08-20 2026-08-20 2 8 8 13 The role of Roziakhon Usmonova in the development of the Uzbek school of scene speech https://integrumpublication.org/index.php/ajste/article/view/300 This article is devoted to a comprehensive study of the life, creative activity and scientific and pedagogical heritage of Roziyakhon Usmonova, a teacher and stage speech teacher who made a worthy contribution to the formation and development of the Uzbek school of stage speech, and who has worked effectively in the theater and cinema arts and higher education system for many years. The article scientifically analyzes the role of the teacher in the formation of national theater art, speech and acting skills, her contribution to improving the culture of stage speech, and her services in training professional actors and directors in the republic. Makhsuma Khodjimatova Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0 2026-08-20 2026-08-20 2 8 14 17 Legal regulation of psychosocial risks in employment relations: the employer’s preventive obligations and improving Uzbekistan’s labour legislation https://integrumpublication.org/index.php/ajste/article/view/301 This article examines the labour-law nature of psychosocial risks and the employer’s preventive obligations. Although Uzbekistan has a Labour Code, the Law On Labour Protection and an occupational risk assessment system, the legislation does not yet clearly establish a specific definition of psychosocial risk, assessment criteria or safeguards for confidential reporting. Based on comparative legal analysis, the article proposes recognising psychosocial risk as an occupational risk, integrating it into the existing risk assessment system, establishing the employer’s obligations within an identification-assessment-prevention-monitoring cycle, and introducing a new Article 359¹ into the Labour Code. Bahodir Mamasharifovich Hamroqulov Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0 2026-08-20 2026-08-20 2 8 18 29 The power of independence https://integrumpublication.org/index.php/ajste/article/view/302 This article examines the historical and contemporary significance of independence in the development of the Republic of Uzbekistan. It highlights the role of independence in strengthening national identity, political sovereignty, economic development, education, public security, and international cooperation. Particular attention is paid to the role of young people and education in ensuring the sustainable development and future prosperity of the country. The article emphasizes that independence is not only a historical achievement but also a responsibility to protect peace, stability, national values, and human rights. It concludes that the power of independence is reflected in Uzbekistan’s ability to determine its own path of development while actively participating in the international community. Munavvar Xaydarovna Rashidova Dilnoza Berdimurotovna Namozova Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0 2026-08-20 2026-08-20 2 8 30 33